U.S. Climbs to No.2 in Crypto Adoption as ETFs Boost Demand.

Chainalysis reports U.S. crypto adoption rose amid recent regulatory momentum, including the approval of spot Bitcoin ETFs.

  • North America moved to the second-highest regional position, with on-chain volume above $2.2 trillion and 49% year‑over‑year growth.
  • Chainalysis added an institutional activity sub-index that counts transfers over $1 million to capture large players.
  • The United States remains the largest fiat on‑ramp with over $4.2 trillion in fiat inflows to crypto exchanges.
  • Stablecoins remain central to market infrastructure, led by USDT and USDC, while new regulated stablecoins have seen rapid growth.

Chainalysis on September 2, 2025 said U.S. crypto adoption rose after a period of regulatory momentum, including the approval of multiple spot bitcoin ETFs, which helped lift North America’s position in the Global Crypto Adoption Index.

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The report shows North America received over $2.2 trillion in on‑chain crypto activity in the 12 months ending June 2025 and that regionwide activity grew 49% year‑over‑year.

Chainalysis ranked the United States second overall in the 2025 index and added a new institutional activity sub‑index that classifies transfers above $1 million as institutional. This change aims to capture large investors, custodians, and professional trading flows.

The report also says the U.S. is the world’s largest fiat on‑ramp, with more than $4.2 trillion in fiat inflows to tracked centralized exchanges, and that bitcoin led fiat purchases globally with over $4.6 trillion in inflows during the same period. (A fiat on‑ramp is a service that lets users buy cryptocurrency with traditional currency.) 

Chainalysis notes stablecoin activity remains dominated by USDT and USDC, even as smaller regulated stablecoins grew quickly; the report links those trends to evolving policy frameworks and mentions the broader stablecoin regulatory landscape and the GENIUS Act as relevant developments.

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The report provides more detail and an interactive country ranking; readers can reserve a copy for the full dataset and methodology.

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